Anti-Human GITR/TNFRSF18 Reference Antibody (AMG 228, RUO) (HP087026)

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货号	HP087026
品牌	abinScience
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
同种型	IgG
克隆号	AMG 228
表达系统	Mammalian cells
靶标	Activation-inducible TNFR family receptor, GITR, TNFRSF18, CD357, Tumor necrosis factor receptor superfamily member 18, AITR, Glucocorticoid-induced TNFR-related protein
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q9Y5U5
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	AMG-228, AMG228, AMG228
背景	Tumor necrosis factor receptor superfamily member 18 (CD357/GITR) is a ~26 kDa protein. Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
文献	1. Tran B, et al. Dose escalation results from a first-in-human, phase 1 study of glucocorticoid-induced TNF receptor-related protein agonist AMG 228 in patients with advanced solid tumors. J Immunother Cancer. 2018 Sep 25;6(1):93. [HP087026]
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD357/TNFRSF18/GITR (AMG 228)
Bioactivity

Detects recombinant human CD357/TNFRSF18/GITR (Catalog No: HV475012) in indirect ELISA

产品说明书

Anti-Human GITR/TNFRSF18 Reference Antibody (AMG 228, RUO).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (起始浓度)

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C₂ (终浓度)

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Anti-Human GITR/TNFRSF18 Reference Antibody (AMG 228, RUO) (HP087026)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human GITR/TNFRSF18 Reference Antibody (AMG 228, RUO) (HP087026)

概述

图片

参考文献

产品说明书

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