| 货号 | MX139016 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Mouse |
| 同种型 | IgG2a-kappa |
| 表达系统 | Mammalian Cells |
| 克隆类型 | Monoclonal |
| 靶标 | T1, DER4, Interleukin-1 receptor-like 1, ST2, IL1RL1, Protein ST2 |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | Q01638 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | AMG-282, MSTT-1041A, RG-6149, RO-7187807, 2173054-79-8 |
| 背景 | Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody that blocks IL-33 signaling by targeting ST2, the IL-33 receptor. Astegolimab has the potential for chronic obstructive pulmonary disease (COPD) research. • T1/ST2--an IL-1 receptor-like modulator of immune responses., PMID:15110792 • The IL-1 receptor-related T1 antigen is expressed on immature and mature mast cells and on fetal blood mast cell progenitors., PMID:9794420 • Identification of the primary growth response gene, ST2/T1, as a gene whose expression is differentially regulated by different protein kinase C isozymes., PMID:7556667 |
| Note | For research use only. |
SDS-PAGE for Research Grade Astegolimab
Detects recombinant human IL1RL1/ST2 (Catalog No: HX139011) in indirect ELISA
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