Anti-Human NKG2D/CD314 Reference Antibody (CYAD-03, RUO) (HB123056)

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概述

货号	HB123056
品牌	abinScience
描述	Anti-Human CD314/KLRK1/NKG2D (CYAD-03) (HB123056) is a research-grade recombinant antibody targeting CD314. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
同种型	IgG
克隆号	CYAD-03
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	KLRK1, NKG2D, Killer cell lectin-like receptor subfamily K member 1, NKG2-D-activating NK receptor, D12S2489E, NKG2-D type II integral membrane protein, NK cell receptor D, CD314
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P26718
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	CYAD-03, CYAD03, CYAD03
背景	NKG2-D type II integral membrane protein (CD314/KLRK1) is a ~25 kDa protein. Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD314/KLRK1/NKG2D (CYAD-03)

参考文献

产品说明书

Anti-Human NKG2D/CD314 Reference Antibody (CYAD-03, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human NKG2D/CD314 Reference Antibody (CYAD-03, RUO) (HB123056)

概述

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参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human NKG2D/CD314 Reference Antibody (CYAD-03, RUO) (HB123056)

概述

图片

参考文献

产品说明书

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