Anti-Human ADCYAP1/PACAP Reference Antibody (Bocunebart, RUO) (HB716046)

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100ug
1mg
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概述
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参考文献
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概述

货号	HB716046
品牌	abinScience
描述	bocunebart (HB716046) is a research-grade recombinant antibody targeting PACAP/ADCYAP1. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research.
种属反应性	Human
应用	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
宿主	Human
克隆类型	Monoclonal
同种型	IgG1, Kappa
种属	Human
靶标	PACAP/ADCYAP1
内毒素水平	< 10 EU/mg
纯度	>95% as determined by SDS-PAGE.
Accession号	P18509
状态	Liquid
保存溶液	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	2984605-64-1
背景	Pituitary adenylate cyclase-activating polypeptide (PACAP/ADCYAP1) is a ~18 kDa protein. PACAP is a neuropeptide involved in diverse array of physiological processes through activating the PACAP subfamily of class B1 G protein-coupled receptors: VIP receptor 1 (VIPR1), VIP receptor 2 (VIPR2), and PACAP type I receptor (ADCYAP1R1). Exerts neuroprotective and general cytoprotective effects due to anti-apoptotic, anti-inflammatory, and antioxidant actions. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells. 1. Inooka, H. et al. (2001) Nature structural biology 8, 161-5. PMID: 11175907 2. Emery, AC. et al. (2013) Science signaling 6, ra51. PMID: 23800469 3. Wang, J. et al. (2020) Cell research 30, 436-445. PMID: 32047270 4. Piper, SJ. et al. (2022) Nature communications 13, 7013. PMID: 36385145
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade bocunebart

参考文献

产品说明书

Anti-Human ADCYAP1/PACAP Reference Antibody (Bocunebart, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ADCYAP1/PACAP Reference Antibody (Bocunebart, RUO) (HB716046)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ADCYAP1/PACAP Reference Antibody (Bocunebart, RUO) (HB716046)

概述

图片

参考文献

产品说明书

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