

| 货号 | HW498036 |
|---|---|
| 品牌 | abinScience |
| 描述 |
birinkibart (HW498036) is a research-grade recombinant antibody targeting CD131.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Human |
| 同种型 | IgG4, Kappa |
| 种属 | Human |
| 克隆类型 | Monoclonal |
| 靶标 | CD131/CSF2RB |
| 内毒素水平 | < 10 EU/mg |
| 纯度 | >95% as determined by SDS-PAGE. |
| Accession号 | P32927 |
| 状态 | Liquid |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | 2894136-82-2 |
| 背景 | Cytokine receptor common subunit beta (CD131/CSF2RB) is a ~97 kDa protein. Cell surface receptor that plays a role in immune response and controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Acts by forming an heterodimeric receptor through interaction with different partners such as IL3RA, IL5RA or CSF2RA. In turn, participates in various signaling pathways including interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor/CSF2 pathways. In unstimulated conditions, interacts constitutively with JAK1 and ligand binding leads to JAK1 stimulation and subsequent activation of the JAK-STAT pathway. 1. Tavernier, J. et al. (1992) Proceedings of the National Academy of Sciences of the United States of America 89, 7041-5. PMID: 1495999 2. Ogata, N. et al. (1998) Blood 91, 2264-71. PMID: 9516124 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade birinkibart



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