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Anti-Human CCL17/TARC Reference Antibody (Denrakibart, RUO) (HV615016)

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规格:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
数量:
  • 概述

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  • 参考文献

  • 产品说明书

概述
货号HV615016
品牌abinScience
描述
denrakibart (HV615016) is a research-grade recombinant antibody targeting CCL17/TARC.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主Human
同种型IgG2, Kappa
种属Human
克隆类型Monoclonal
靶标CCL17/TARC
内毒素水平< 10 EU/mg
纯度>95% as determined by SDS-PAGE.
Accession号Q92583
状态Liquid
重悬Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名2922866-66-6
背景

C-C motif chemokine 17 (CCL17/TARC) is a ~10 kDa protein. Chemokine, which displays chemotactic activity for T lymphocytes, preferentially Th2 cells, but not monocytes or granulocytes. Therefore plays an important role in a wide range of inflammatory and immunological processes. Acts by binding to CCR4 at T-cell surface. Mediates GM-CSF/CSF2-driven pain and inflammation. In the brain, required to maintain the typical, highly branched morphology of hippocampal microglia under homeostatic conditions.

1. Imai, T. et al. (1996) The Journal of biological chemistry 271, 21514-21. PMID: 8702936
2. Imai, T. et al. (1997) The Journal of biological chemistry 272, 15036-42. PMID: 9169480
3. Garlisi, CG. et al. (1999) European journal of immunology 29, 3210-5. PMID: 10540332
4. Achuthan, A. et al. (2016) The Journal of clinical investigation 126, 3453-66. PMID: 27525438
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • SDS-PAGE

    SDS-PAGE for Research Grade denrakibart

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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