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Anti-Human TWEAK/TNFSF12 Reference Antibody (BIIB023, RUO) (HT065016)

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规格:
  • 100ug
  • 1mg
  • 5mg
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  • 参考文献

  • 产品说明书

概述
货号HT065016
品牌abinScience
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主Human
同种型IgG1-kappa
克隆号BIIB023
表达系统Mammalian cells
克隆类型Monoclonal
靶标TWEAK, DR3LG, TNFSF12, Tumor necrosis factor ligand superfamily member 12, APO3L, TNF-related weak inducer of apoptosis, APO3 ligand
内毒素水平< 10 EU/mg
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号O43508
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名BIIB023, DHK29401
背景

Tumor necrosis factor ligand superfamily member 12 (CD255/TNFSF12) is a ~27 kDa protein. Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines.

文献1. Galluppi GR, et al. Population pharmacokinetic and pharmacodynamic analysis of BIIB023, an anti-TNF-like weak inducer of apoptosis (anti-TWEAK) monoclonal antibody. Br J Clin Pharmacol. 2016 Jul;82(1):118-28. [HT065016]
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human TWEAK/TNFSF12 (BIIB023)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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