| 货号 | HB754026 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Human |
| 同种型 | IgG1-kappa |
| 表达系统 | Mammalian Cells |
| 克隆类型 | Monoclonal |
| 靶标 | Emfilermin, D factor, HILDA, LIF, MLPLI, Melanoma-derived LPL inhibitor, Leukemia inhibitory factor, Differentiation-stimulating factor |
| 内毒素水平 | Please contact the lab for this information. |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P15018 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 别名 | 2740565-02-8 |
| 背景 | Falbikitug is a humanized immunoglobulin G1-kappa, anti-LIF monoclonal antibody. Falbikitug is an antineoplastic. • Leukemia inhibitory factor (LIF)., PMID:26187859 • Biomolecular Markers of Recurrent Implantation Failure-A Review., PMID:34576245 • Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring., PMID:30996350 • Augmentative effects of leukemia inhibitory factor reveal a critical role for TYK2 signaling in vascular calcification., PMID:39084258 • Nephron induction., PMID:12386301 • p53 and reproduction., PMID:29307398 • A peptide derived from the CD loop-D helix region of ciliary neurotrophic factor (CNTF) induces neuronal differentiation and survival by binding to the leukemia inhibitory factor (LIF) receptor and common cytokine receptor chain gp130., PMID:22000729 • Therapeutic Targeting of LIF Overcomes Macrophage-mediated Immunosuppression of the Local Tumor Microenvironment., PMID:36441800 • TGF-β-driven LIF expression influences neutrophil extracellular traps (NETs) and contributes to peritoneal metastasis in gastric cancer., PMID:38490994 • Super-Enhancer Driven LIF/LIFR-STAT3-SOX2 Regulatory Feedback Loop Promotes Cancer Stemness in Head and Neck Squamous Cell Carcinoma., PMID:39206755 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Falbikitug.
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