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Research Grade Nolavetbart (CV121016)

价格:
规格:
  • 100ug
  • 1mg
数量:
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概述
货号CV121016
品牌abinScience
种属反应性Dog
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主Dog
同种型IgG2-kappa
表达系统Mammalian Cells
克隆类型Monoclonal
靶标IL31RA
内毒素水平Please contact the lab for this information.
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号A0A8I3Q391
状态Liquid
保存溶液0.01M PBS, pH 7.4.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
别名2750248-93-0
背景Nolavetbart is an anti-Canlupfam IL31RA human IgG2 κ monoclonal antibody. Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).
• Oncostatin M suppresses IL31RA expression in dorsal root ganglia and interleukin-31-induced itching., PMID:38035099
• Nemolizumab: First Approval., PMID:35834124
• IL-31-dependent neurogenic inflammation restrains cutaneous type 2 immune response in allergic dermatitis., PMID:37831760
• Interleukin-31: The "itchy" cytokine in inflammation and therapy., PMID:33629401
• Phase 3 Trial of Nemolizumab in Patients with Prurigo Nodularis., PMID:37888917
• Lineage-specific regulatory changes in hypertrophic cardiomyopathy unraveled by single-nucleus RNA-seq and spatial transcriptomics., PMID:36646705
• Prurigo nodularis: new insights into pathogenesis and novel therapeutics., PMID:38345154
• Mechanisms and treatments of neuropathic itch in a mouse model of lymphoma., PMID:36520531
• A sensory neuron-expressed IL-31 receptor mediates T helper cell-dependent itch: Involvement of TRPV1 and TRPA1., PMID:24373353
• Genetic association of IL2RA, IL17RA, IL23R, and IL31RA single nucleotide polymorphisms with alopecia areata., PMID:36248775
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
参考文献

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