Anti-Human LILRB4/CD85k/ILT3 Reference Antibody (Rolistobart, RUO) (HV126046)

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概述

货号	HV126046
品牌	abinScience
描述	Rolistobart (HV126046) is a research-grade recombinant antibody targeting CD85. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
同种型	IgG4-kappa
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	CD85 antigen-like family member K, LIR-5, Leukocyte immunoglobulin-like receptor 5, ILT3, ILT-3, Immunoglobulin-like transcript 3, LILRB4, CD85k, Leukocyte immunoglobulin-like receptor subfamily B member 4, Monocyte inhibitory receptor HM18, LIR5
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q8NHJ6
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	2723442-10-0
背景	Leukocyte immunoglobulin-like receptor subfamily B member 4 (CD85k/LILRB4) is a ~49 kDa protein. Inhibitory receptor involved in the down-regulation of the immune response and the development of immune tolerance. Receptor for FN1. Receptor for apolipoprotein APOE. Receptor for ALCAM/CD166. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. 1. Chang, CC. et al. (2002) Nature immunology 3, 237-43. PMID: 11875462 2. Su, MT. et al. (2021) International immunology 33, 447-458. PMID: 34089617 3. Deng, M. et al. (2018) Nature 562, 605-609. PMID: 30333625 4. Xu, Z. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 1207-1219. PMID: 29263213 5. Cella, M. et al. (1997) The Journal of experimental medicine 185, 1743-51. PMID: 9151699 6. Lu, HK. et al. (2009) The Journal of biological chemistry 284, 34839-48. PMID: 19833736 7. Kim-Schulze, S. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 176, 2790-8. PMID: 16493035
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Anti-Human LILRB4/CD85k/ILT3 Reference Antibody (Rolistobart, RUO)

参考文献

产品说明书

Anti-Human LILRB4/CD85k/ILT3 Reference Antibody (Rolistobart, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

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Anti-Human LILRB4/CD85k/ILT3 Reference Antibody (Rolistobart, RUO) (HV126046)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human LILRB4/CD85k/ILT3 Reference Antibody (Rolistobart, RUO) (HV126046)

概述

图片

参考文献

产品说明书

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