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Research Grade Berahyaluronidase Alfa (HW825016)

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概述
货号HW825016
品牌abinScience
描述
Berahyaluronidase Alfa (HW825016) is a research-grade recombinant antibody targeting Hyaluronidase PH-20. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性Human
应用ELISA, Functional assay, Research in vivo
克隆类型Monoclonal
同种型Human hyaluronidase isozyme-5/HYAL5 fragment engineered variant with the structural domain replaced by the corresponding region of human hyaluronidase isozyme-1/HYAL1.
表达系统Mammalian cells
靶标Hyaluronidase PH-20, Sperm surface protein PH-20, HYAL3, Sperm adhesion molecule 1, PH20, SPAM1, Hyal-PH20, Hyaluronoglucosaminidase PH-20
内毒素水平< 10 EU/mg as determined by LAL method.
纯度>95% purity as determined by SDS-PAGE.
纯化方式Purified by Nickel column.
Accession号P38567
状态Liquid
保存溶液 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名2636716-20-4
背景

Hyaluronidase PH-20 (SPAM1) is a ~57 kDa protein. Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid.

NoteFor research use only. Not suitable for clinical or therapeutic use.
图片

  • SDS-PAGE

    SDS-PAGE for Research Grade Berahyaluronidase Alfa

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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