



| 货号 | VK698016 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Traxivitug (VK698016) is a research-grade recombinant antibody targeting Major capsid protein VP1. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 种属反应性 | BK polyomavirus (BKPyV) |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Human |
| 同种型 | IgG1-lambda2 |
| 表达系统 | Mammalian cells |
| 克隆类型 | Monoclonal |
| 靶标 | Major capsid protein VP1, Major structural protein VP1 |
| 内毒素水平 | < 10 EU/mg |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P03088 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | 2770852-89-4, MAU868 |
| 背景 | Major capsid protein VP1 is a ~40 kDa protein. Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins. Interacts with gangliosides GT1b and GD1b containing terminal alpha(2-8)-linked sialic acids on the cell surface to provide virion attachment to target cell. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis and traffics to the endoplasmic reticulum. Inside the endoplasmic reticulum, the protein folding machinery isomerizes VP1 interpentamer disulfide bonds, thereby triggering initial uncoating. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Traxivitug.

Detects recombinant BKPyV VP1 (Catalog No: VK452011) in indirect ELISA.





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