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Anti-Human Lymphotoxin beta R/TNFRSF3 Reference Antibody (CBE-11, RUO) (HW495016)

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规格:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
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数量:
  • 概述

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  • 参考文献

  • 产品说明书

概述
货号HW495016
品牌abinScience
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主Human
同种型IgG1-kappa
克隆号CBE-11
表达系统Mammalian cells
克隆类型Monoclonal
靶标Tumor necrosis factor receptor superfamily member 3, Lymphotoxin-beta receptor, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, Tumor necrosis factor receptor type III, TNF-RIII, TNFR-III, LTBR, D12S370, TNFCR, TNFR3, TNFRSF3
内毒素水平< 10 EU/mg
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P36941
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名hCBE-11, CBE-11, HCBE11, CBE11, CBE11
背景

Tumor necrosis factor receptor superfamily member 3 (LTBR/TNFR-III) is a ~46 kDa protein. Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Activates NF-kappa-B signaling pathway upon stimulation with lymphotoxin (LTA(1)-LTB(2)). Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs.

1. Sudhamsu, J. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 19896-901. PMID: 24248355
文献1. Lukashev M, et al. Targeting the lymphotoxin-beta receptor with agonist antibodies as a potential cancer therapy. Cancer Res. 2006 Oct 1;66(19):9617-24. [HW495016]
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • SDS-PAGE

    SDS-PAGE for Research Grade Anti-Human LTBR/TNFR-III Antibody (CBE-11)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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