Anti-Human Activin Receptor IIB Reference Antibody (KER-012, RUO) (HC570026)

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概述

货号	HC570026
品牌	abinScience
描述	Anti-Human ACVR2B Antibody (KER-012) (HC570026) is a research-grade recombinant antibody targeting ACTR-IIB. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human
应用	ELISA, Functional assay, Research in vivo
同种型	Fusion-[human ACTR-IIB]2-Fc (Fragment constant)
克隆号	KER-012
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	ACTR-IIB, Activin receptor type IIB, Activin receptor type-2B, ACVR2B
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	Q13705
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	KER012, RKER-012, RKER012
背景	Activin receptor type-2B (ACVR2B) is a ~57 kDa protein. Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary. Within the receptor complex, the type-2 receptors act as a primary activin receptors (binds activin-A/INHBA, activin-B/INHBB as well as inhibin-A/INHA-INHBA). The type-1 receptors like ACVR1B act as downstream transducers of activin signals.
Note	For research use only. Not suitable for clinical or therapeutic use.

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参考文献

产品说明书

Anti-Human Activin Receptor IIB Reference Antibody (KER-012, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

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抗体

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Anti-Human Activin Receptor IIB Reference Antibody (KER-012, RUO) (HC570026)

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重组蛋白

抗体

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实验相关试剂

Anti-Human Activin Receptor IIB Reference Antibody (KER-012, RUO) (HC570026)

概述

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参考文献

产品说明书

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