

| 货号 | HF990046 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | ELISA, Functional assay, Research in vivo |
| 同种型 | Recombinant human Insulin analogue |
| 生物活性 | Insulin cattle is the two-chain polypeptide hormone produced by the β-cells of pancreatic islets. The α and β chains are joined by two interchain disulfide bonds. The α chain contains an intrachain disulfide bond. Insulin regulates glucose uptake into muscle and fat cells by recruiting membrane glucose transporter Glut-4 to cell surface. Insulin cattle has often been used as growth supplement in culturing cells at the concentration ranging from 1 to 10 ug/mL of medium [1]. in the pancreatic β cells. Insulin cattle has often been used as growth supplement in culturing cells. |
| 表达系统 | Mammalian cells |
| 靶标 | INS, Insulin |
| 内毒素水平 | < 10 EU/mg |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Purified by Nickel column. |
| Accession号 | P01308 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | NN1250, NN-1250, 2381089-83-2 |
| 背景 | Insulin is a ~11 kDa protein. Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. |
| 文献 | 1. Yousefi R, et al. Aspirin-mediated acetylation induces structural alteration and aggregation of bovine pancreaticinsulin. J Biomol Struct Dyn. 2016;34(2):362-75. [HF990046] |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

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