| 货号 | HB771016 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Humanized |
| 同种型 | IgG1-kappa |
| 表达系统 | Mammalian Cells |
| 种属 | Human |
| 克隆类型 | Monoclonal |
| 靶标 | T-cell growth factor P40, Cytokine P40, IL9, Interleukin-9, IL-9 |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P15248 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 别名 | 7F3com-2H2, MEDI-528, 909875-08-7 |
| 背景 | Enokizumab (MEDI-528) is a monoclonal antibody targeting to interleukin (IL)-9. IL-9 regulates the development of airway inflammation, mucus production, airway hyperresponsiveness, and airway fibrosis largely by increasing mast cell numbers and activity in the airways. • IL-9 secreted by leukemia stem cells induces Th1-skewed CD4+ T cells, which promote their expansion., PMID:38941612 • Positive feedback loop PU.1-IL9 in Th9 promotes rheumatoid arthritis development., PMID:39164066 • The Role of Interleukin-9 in Cancer., PMID:31016637 • IL-9, a local growth factor for synovial T cells in inflammatory arthritis., PMID:26751012 • Locus of (IL-9) control: IL9 epigenetic regulation in cellular function and human disease., PMID:38825637 • Interleukin-9 and mast cells., PMID:23034251 • IL-9 sensitizes human TH2 cells to proinflammatory IL-18 signals in atopic dermatitis., PMID:39521283 • IL-9 and IL-9-producing cells in tumor immunity., PMID:32228589 • Interleukin-9 and T helper type 9 cells in rheumatic diseases., PMID:27159882 • IL-9-producing T cells: potential players in allergy and cancer., PMID:32788707 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
SEC-HPLC detection for Research Grade Enokizumab.
SDS-PAGE for Research Grade Enokizumab.
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