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Research Grade Lebrikizumab (HW632026)

价格:
规格:
  • 100ug
  • 1mg
数量:
  • 概述
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  • 参考文献
  • 产品说明书
概述
货号HW632026
品牌abinScience
种属反应性Human
应用Research Grade Biosimilar
宿主Humanized
同种型IgG4-kappa
表达系统Mammalian Cells
种属Human
克隆类型Monoclonal
靶标IL13, NC30, Interleukin-13, IL-13
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P35225
状态Liquid
保存溶液0.01M PBS, pH 7.4.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
别名MILR1444A, PRO301444, CAS: 953400-68-5
背景Lebrikizumab (TNX-650) is an IgG4 humanized anti-interleukin-13 (IL-13) mAb with anti-itch effects that specifically binds to IL-13 in a non-receptor binding domain and inhibits its function. Lebrikizumab inhibits the IL-13 driven Th2 inflammatory response and blocks the signaling of IL-4Rα/IL-13Rα1. Lebrikizumab can be used for the research of asthma, atopic dermatitis and neuroinflammatory diseases.
NoteFor research use only. Not suitable for clinical or therapeutic use.
图片
  • Bioactivity

    Detects Human IL13 in indirect ELISAs.

参考文献

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