货号 | HW632026 |
---|---|
品牌 | abinScience |
种属反应性 | Human |
应用 | Research Grade Biosimilar |
宿主 | Humanized |
同种型 | IgG4-kappa |
表达系统 | Mammalian Cells |
种属 | Human |
克隆类型 | Monoclonal |
靶标 | IL13, NC30, Interleukin-13, IL-13 |
内毒素水平 | Please contact with the lab for this information. |
纯度 | >95% as determined by SDS-PAGE. |
纯化方式 | Protein A/G purified from cell culture supernatant. |
Accession号 | P35225 |
状态 | Liquid |
保存溶液 | 0.01M PBS, pH 7.4. |
稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
别名 | MILR1444A, PRO301444, CAS: 953400-68-5 |
背景 | Lebrikizumab (TNX-650) is an IgG4 humanized anti-interleukin-13 (IL-13) mAb with anti-itch effects that specifically binds to IL-13 in a non-receptor binding domain and inhibits its function. Lebrikizumab inhibits the IL-13 driven Th2 inflammatory response and blocks the signaling of IL-4Rα/IL-13Rα1. Lebrikizumab can be used for the research of asthma, atopic dermatitis and neuroinflammatory diseases. |
Note | For research use only. Not suitable for clinical or therapeutic use. |
Detects Human IL13 in indirect ELISAs.
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