| 货号 | HF909026 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Human |
| 同种型 | IgG4-kappa |
| 表达系统 | Mammalian Cells |
| 种属 | Human |
| 克隆类型 | Monoclonal |
| 靶标 | Beta-nerve growth factor, NGFB, Beta-NGF, NGF |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P01138 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 别名 | REGN475, SAR164877, 1190239-42-9 |
| 背景 | Luvagrobart is an anti-NGF human IgG1 κ monoclonal antibody. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). • Nerve growth factor β polypeptide (NGFB) genetic variability: association with the methadone dose required for effective maintenance treatment., PMID:21358750 • Nerve growth factor R221W responsible for insensitivity to pain is defectively processed and accumulates as proNGF., PMID:19038341 • Rare human nerve growth factor-β mutation reveals relationship between C-afferent density and acute pain evaluation., PMID:27146986 • Genomic NGFB variation and multiple sclerosis in a case control study., PMID:19063739 • A novel NGFB point mutation: a phenotype study of heterozygous patients., PMID:18420729 • Variation in the BDNF and NGFB genes in German atopic dermatitis patients., PMID:19038326 • Variation in NGFB is associated with primary affective disorders in women., PMID:21294249 • Association of NTRK3 and its interaction with NGF suggest an altered cross-regulation of the neurotrophin signaling pathway in eating disorders., PMID:18203754 • In vitro receptor binding properties of a "painless" NGF mutein, linked to hereditary sensory autonomic neuropathy type V., PMID:19945432 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
SEC-HPLC detection for Research Grade Fasinumab.
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