

| 货号 | HB732206 |
|---|---|
| 品牌 | abinScience |
| 描述 |
gimvekibart (HB732206) is a research-grade recombinant antibody targeting CD124.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, FACS, Functional assay |
| 宿主 | Human |
| 同种型 | IgG4, kappa |
| 靶标 | CD124/IL4R/IL-4Rα |
| 内毒素水平 | < 10 EU/mg |
| 纯度 | >95% as determined by SDS-PAGE |
| Accession号 | P24394 |
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | CAS: 3037526-90-9 |
| 背景 | Interleukin-4 receptor subunit alpha is a ~89 kDa protein. Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. 1. Andrews, AL. et al. (2006) The Journal of allergy and clinical immunology 118, 858-65. PMID: 17030238 |
| Note | For research use only. |

SDS-PAGE for Research Grade gimvekibart



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