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Anti-Human SIRP alpha/CD172a Reference Antibody (Ipsoprubart, RUO) (HX892146)

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概述
货号HX892146
品牌abinScience
描述
ipsoprubart (HX892146) is a research-grade recombinant antibody targeting CD172.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
种属反应性Human
应用ELISA, FACS, Functional assay
宿主Human
同种型IgG1, kappa
靶标CD172a/SIRPA
内毒素水平< 10 EU/mg
纯度>95% as determined by SDS-PAGE
Accession号P78324
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名CAS: 3035552-25-8
背景

Tyrosine-protein phosphatase non-receptor type substrate 1 is a ~54 kDa protein. Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin.

1. Yao, M. et al. (2014) Journal of the American Society of Nephrology : JASN 25, 1171-86. PMID: 24511121
NoteFor research use only.
图片

  • SDS-PAGE

    SDS-PAGE for Research Grade ipsoprubart

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human SIRP alpha/CD172a Reference Antibody (Ipsoprubart, RUO)

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