Anti-Human Integrin alpha L/CD11a Reference Antibody (Odulimomab, RUO) (HB805026)

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概述

货号	HB805026
品牌	abinScience
描述	Research Grade Odulimomab (HB805026) is a mouse monoclonal antibody detecting CD11A in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human. Highlights ●Multi-Application — Validated across multiple applications.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
同种型	IgG1, kappa
表达系统	Mammalian cells
种属	Human
靶标	CD11A, Leukocyte function-associated molecule 1 alpha chain, Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, CD11 antigen-like family member A, CD11a, ITGAL, Integrin alpha-L
内毒素水平	< 10 EU/mg
纯度	>95% as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P20701
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	afolimomab, anti-LFA1, 159445-64-4
背景	Integrin alpha-L (CD11A,Leukocyte function-associated molecule 1 alpha chain,Leukocyte adhesion glycoprotein LFA-1 alpha chain,LFA-1A,CD11 antigen-like family member A,ITGAL,Integrin alpha-L) is a ~128 kDa protein. Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is a receptor for F11R. Integrin ITGAL/ITGB2 is a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity. 1. Hermand, P. et al. (2000) The Journal of biological chemistry 275, 26002-10. PMID: 10846180 2. Shimaoka, M. et al. (2003) Cell 112, 99-111. PMID: 12526797 3. de Fougerolles, AR. et al. (1991) The Journal of experimental medicine 174, 253-67. PMID: 1676048 4. Dustin, ML. et al. (1986) Journal of immunology (Baltimore, Md. : 1950) 137, 245-54. PMID: 3086451 5. Ostermann, G. et al. (2002) Nature immunology 3, 151-8. PMID: 11812992 6. Fraemohs, L. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 6259-64. PMID: 15528364 7. Swaim, CD. et al. (2017) Molecular cell 68, 581-590.e5. PMID: 29100055 8. Barber, DF. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 3653-9. PMID: 15356110 9. Lacouture, C. et al. (2024) Nature communications 15, 407. PMID: 38195629 10. Kristóf, E. et al. (2013) Apoptosis : an international journal on programmed cell death 18, 1235-51. PMID: 23775590
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)

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SDS-PAGE

SDS-PAGE for Research Grade Odulimomab

参考文献

产品说明书

Anti-Human Integrin alpha L/CD11a Reference Antibody (Odulimomab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

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Anti-Human Integrin alpha L/CD11a Reference Antibody (Odulimomab, RUO) (HB805026)

概述

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参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Integrin alpha L/CD11a Reference Antibody (Odulimomab, RUO) (HB805026)

概述

图片

参考文献

产品说明书

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