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Research Grade Atibuclimab (HY038016)

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规格:
  • 100ug
  • 1mg
数量:
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概述
货号HY038016
品牌abinScience
种属反应性Human
应用Research Grade Biosimilar
宿主Chimeric
同种型IgG4-kappa
表达系统Mammalian Cells
种属Human
克隆类型Monoclonal
靶标Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P08571
状态Liquid
保存溶液0.01M PBS, pH 7.4.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
别名28C5, termed IC14, CAS: 2417175-94-9
背景Atibuclimab, is a chimeric monoclonal antibody directed against CD14 and is composed of murine variable and human IgG4 Fc regions. Atibuclimab can be used for the research of amyotrophic lateral sclerosis. Atibuclimab attenuates LPS-induced symptoms and strongly inhibits LPS-induced proinflammatory cytokine release, while only delaying the release of the anti-inflammatory cytokines soluble TNF receptor type I and IL-1 receptor antagonist.
NoteFor research use only. Not suitable for clinical or therapeutic use.
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