Anti-Human Complement C5 Reference Antibody (Ascuprubart, RUO) (HF687196)

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概述
图片
参考文献
产品说明书

概述

货号

HF687196

品牌

abinScience

描述

Research Grade ascuprubart (HF687196) is a human monoclonal antibody. Suitable for Human.

种属反应性

Human

应用

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

宿主

Human

同种型

IgG H-gamma2-4 chimerisotype G2[11aaG4]-kappa

克隆类型

Monoclonal

内毒素水平

< 10 EU/mg

纯度

>95% as determined by SDS-PAGE.

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

P01031

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Complement C5 (ComplementC5) is a ~188 kDa protein. Precursor of the C5a anaphylatoxin and complement C5b components of the complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Activated downstream of classical, alternative, lectin and GZMK complement pathways.

1. Rawal, N. et al. (2003) The Journal of biological chemistry 278, 38476-83. PMID: 12878586

2. Rawal, N. et al. (2008) The Journal of biological chemistry 283, 7853-63. PMID: 18204047

3. Heesterbeek, DA. et al. (2019) The EMBO journal 38. PMID: 30643019

4. DiScipio, RG. et al. (1983) The Journal of biological chemistry 258, 10629-36. PMID: 6554279

5. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456

6. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human Complement C5 Reference Antibody (Ascuprubart, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Complement C5 Reference Antibody (Ascuprubart, RUO) (HF687196)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Complement C5 Reference Antibody (Ascuprubart, RUO) (HF687196)

概述

图片

参考文献

产品说明书

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