

| 货号 | HY286166 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 描述 |
Research Grade dulpatatug (HY286166) is a human monoclonal antibody. Suitable for Human.
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| 种属反应性 | Human | ||||
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo | ||||
| 宿主 | Human | ||||
| 同种型 | IgG1, kappa | ||||
| 克隆类型 | Monoclonal | ||||
| 内毒素水平 | < 10 EU/mg | ||||
| 纯度 | >95% as determined by SDS-PAGE. | ||||
| 纯化方式 | Protein A/G purified from cell culture supernatant. | ||||
| Accession号 | P04626 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Receptor tyrosine-protein kinase erbB-2 (CD340/ERBB2) is a ~137 kDa protein. Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. | ||||
| Note | For research use only. |

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