Anti-Human CD40/TNFRSF5 Reference Antibody (Selicrelumab, RUO) (HB782036)

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概述
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产品说明书

概述

货号	HB782036
品牌	abinScience
描述	Selicrelumab (HB782036) is a research-grade recombinant antibody targeting CD40. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
宿主	Human
同种型	IgG2-kappa
表达系统	Mammalian cells
克隆类型	Monoclonal
靶标	Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, TNFRSF5, CDw40, CD40
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P25942
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	CP-870, 893, RG-7876, RO-7009789, 1622140-49-1
背景	Tumor necrosis factor receptor superfamily member 5 (CD40/TNFRSF5) is a ~30 kDa protein. Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. 1. Takada, YK. et al. (2019) Journal of immunology (Baltimore, Md. : 1950) 203, 1383-1391. PMID: 31331973
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

Detects CD40/TNFRSF5 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Anti-Human CD40/TNFRSF5 Reference Antibody (Selicrelumab, RUO)

参考文献

产品说明书

Anti-Human CD40/TNFRSF5 Reference Antibody (Selicrelumab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD40/TNFRSF5 Reference Antibody (Selicrelumab, RUO) (HB782036)

概述

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参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CD40/TNFRSF5 Reference Antibody (Selicrelumab, RUO) (HB782036)

概述

图片

参考文献

产品说明书

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