Anti-Human Integrin alpha 2/CD49b Reference Antibody (Vatelizumab, RUO) (HB772016)

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概述

货号	HB772016
品牌	abinScience
描述	Vatelizumab (HB772016) is a research-grade recombinant antibody targeting CD49B. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性	Human
应用	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
同种型	IgG4-kappa
表达系统	Mammalian cells
靶标	Collagen receptor, ITGA2, VLA-2 subunit alpha, CD49B, CD49 antigen-like family member B, Platelet membrane glycoprotein Ia, GPIa, Integrin alpha-2, CD49b
内毒素水平	< 10 EU/mg
纯度	>95% purity as determined by SDS-PAGE.
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P17301
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	GBR500, 1238217-55-4
背景	Integrin alpha-2 (CD49b/ITGA2) is a ~129 kDa protein. Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
Note	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)

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SDS-PAGE

SDS-PAGE for Research Grade Vatelizumab.
Flow CytoMetry

Flow-cytometry using APC anti-human CD49b antibody. HUVEC cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD49b monoclonal antibody (Catalog: HB772016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
Flow CytoMetry

Flow-cytometry using FITC anti-human CD49b antibody. HUVEC cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human CD49b monoclonal antibody (Catalog: HB772016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
Flow CytoMetry

Flow-cytometry using PE anti-human CD49b antibody. HUVEC cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD49b monoclonal antibody (Catalog: HB772016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

参考文献

产品说明书

Anti-Human Integrin alpha 2/CD49b Reference Antibody (Vatelizumab, RUO).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

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抗体

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Anti-Human Integrin alpha 2/CD49b Reference Antibody (Vatelizumab, RUO) (HB772016)

概述

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参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Integrin alpha 2/CD49b Reference Antibody (Vatelizumab, RUO) (HB772016)

概述

图片

参考文献

产品说明书

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