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Anti-Human CEACAM‑8/CD66b Reference Antibody (Besilesomab, RUO) (HB202016)

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  • 产品说明书

概述
货号HB202016
品牌abinScience
描述
Besilesomab (HB202016) is a research-grade recombinant antibody targeting CD67. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
种属反应性Human
应用ELISA, Bioactivity: FACS, Functional assay, Research in vivo
同种型IgG1-kappa
表达系统Mammalian cells
靶标CD67 antigen, Carcinoembryonic antigen CGM6, Carcinoembryonic antigen-related cell adhesion molecule 8, CGM6, CD66b, Non-specific cross-reacting antigen NCA-95, CEACAM8
内毒素水平< 10 EU/mg
纯度>95% purity as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P31997
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名BW250/183, 537694-98-7
背景

Cell adhesion molecule CEACAM8 (CD66b) is a ~38 kDa protein. Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils.

1. Kuroki, M. et al. (2001) Journal of leukocyte biology 70, 543-50. PMID: 11590190
2. Oikawa, S. et al. (1991) The Journal of biological chemistry 266, 7995-8001. PMID: 2022629
3. Yamanaka, T. et al. (1996) Protein expression and purification 7, 438-46. PMID: 8776764
NoteFor research use only. Not suitable for clinical or therapeutic use.
Isotype ControlMouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)
图片

  • Bioactivity

    Detects CD66b/CEACAM8 in indirect ELISAs.

  • SDS-PAGE

    SDS-PAGE for Research Grade Besilesomab

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human CEACAM‑8/CD66b Reference Antibody (Besilesomab, RUO)

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