| 货号 | HY546016 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Humanized |
| 同种型 | IgG1-kappa |
| 表达系统 | Mammalian Cells |
| 克隆类型 | Monoclonal |
| 靶标 | Meconium antigen 100, CEACAM5, CEA, CD66e, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen |
| 内毒素水平 | Please contact the lab for this information. |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | P06731 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 别名 | hMN14, IMMU-130, hMN-14-SN-38, hMN-14-SN-38ADC, hMN14-CL-SN-38, LabetuzumabGovitecan, 219649-07-7 |
| 背景 | HY-P990940 is an CEACAM5-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001). • Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis., PMID:23903773 • Platelet Carcinoembryonic Antigen Cell Adhesion Molecule 5 (CEACAM5) as a Possible Novel Diagnostic Tool for Evaluation of Acute Coronary Syndrome., PMID:31865362 • Carcinoembryonic Antigen-Related Cell Adhesion Molecule Type 5 Receptor-Targeted Fluorescent Intraoperative Molecular Imaging Tracer for Lung Cancer: A Nonrandomized Controlled Trial., PMID:36705924 • CEACAM5 stimulates the progression of non-small-cell lung cancer by promoting cell proliferation and migration., PMID:32993395 • A highly-specific fully-human antibody and CAR-T cells targeting CD66e/CEACAM5 are cytotoxic for CD66e-expressing cancer cells in vitro and in vivo., PMID:34740610 • CEACAM5 inhibits the lymphatic metastasis of head and neck squamous cell carcinoma by regulating epithelial-mesenchymal transition via inhibiting MDM2., PMID:36377775 • Specific Binding to Differentially Expressed Human Carcinoembryonic Antigen-Related Cell Adhesion Molecules Determines the Outcome of Neisseria gonorrhoeae Infections along the Female Reproductive Tract., PMID:29760215 • Trajectories of Perioperative Serum Tumor Markers and Colorectal Cancer Outcomes: A Retrospective, Multicenter Longitudinal Cohort Study., PMID:34801967 • Detection and clinical significance of CEACAM5 methylation in colorectal cancer patients., PMID:37942534 • CEACAM5 and CEACAM6 are major target genes for Smad3-mediated TGF-beta signaling., PMID:17653079 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
Detects Human CD66e/CEA/CEACAM5 in indirect ELISAs.
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