| 货号 | HC609016 |
|---|---|
| 品牌 | abinScience |
| 种属反应性 | Human |
| 应用 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 宿主 | Human |
| 同种型 | IgG1-kappa |
| 表达系统 | Mammalian Cells |
| 克隆类型 | Monoclonal |
| 靶标 | CD136, Macrophage-stimulating protein receptor, PTK8, MST1R, p185-Ron, RON, CDw136, MSP receptor, Protein-tyrosine kinase 8 |
| 内毒素水平 | Please contact the lab for this information. |
| 纯度 | >95% purity as determined by SDS-PAGE. |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| Accession号 | Q04912 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 别名 | IMCRON-8, RON8, 1188275-92-4 |
| 背景 | Narnatumab (IMC-RON8) is a neutralizing human monoclonal antibody that blocks RON binding to its ligand, macrophage-stimulating protein (MSP), with a Kd of 32 pM. Narnatumab can be used for the research of cancer. • Macrophage-stimulating protein and RON receptor tyrosine kinase: potential regulators of macrophage inflammatory activities., PMID:12472665 • Macrophage stimulating protein., PMID:10549357 • MSP-RON Pathway: Potential Regulator of Inflammation and Innate Immunity., PMID:33117355 • An Introduction and Overview of RON Receptor Tyrosine Kinase Signaling., PMID:36833444 • Oncogenic and invasive potentials of human macrophage-stimulating protein receptor, the RON receptor tyrosine kinase., PMID:12807733 • Roles of macrophage stimulating protein and tyrosine kinase receptor RON in smoke-induced airway inflammation of rats., PMID:26464622 • Kinases involved in MSP/RON signaling., PMID:10080538 • Role of macrophage-stimulating protein and its receptor, RON tyrosine kinase, in ciliary motility., PMID:9045873 • MSP-RON signalling in cancer: pathogenesis and therapeutic potential., PMID:23792360 • The ron receptor tyrosine kinase: a key regulator of inflammation and cancer progression., PMID:24266348 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Narnatumab.
Flow-cytometry using PE anti-human CD136 antibody. SW480 cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD136 monoclonal antibody (Catalog: HC609016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
7X24小时产品咨询热线：027--87433958(9:00-18:00)，或扫描下方产品专员二维码或在线留言
武汉东湖新技术开发区神墩四路666号研发楼B区3层东
24小时产品查询
扫一扫关注我们
专属渠道经理
