货号 | HB613036 |
---|---|
品牌 | abinScience |
种属反应性 | Human |
应用 | Research Grade Biosimilar |
宿主 | Human |
同种型 | IgG4-kappa |
表达系统 | Mammalian Cells |
克隆类型 | Monoclonal |
靶标 | FDC, LAG3, Lymphocyte activation gene 3 protein, CD223, sLAG-3, LAG-3 |
内毒素水平 | Please contact the lab for this information. |
纯度 | >95% purity as determined by SDS-PAGE. |
纯化方式 | Protein A/G, purified from cell culture supernatant. |
Accession号 | P18627 |
状态 | Liquid |
保存溶液 | 0.01M PBS,pH7.4. |
稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
别名 | BMS-986016,ONO-4482,CAS:1673516-98-7 |
背景 | Relatlimab (BMS-986016) is a human monoclonal antibody anti-LAG-3 antibody generated by immunization of transgenic mice bearing human immunoglobulin miniloci with recombinant LAG-3 protein. Relatlimab blocks LAG-3/MHC II interaction with an IC50 value of 0.67 nM and LAG-3/FGL1 interaction with an IC50 value of 0.019 nM. Relatlimab can be used in research of cancer. |
Note | For research use only. Not for use in clinical or therapeutic applications. |
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