

| 货号 | PX-P6186 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Recombinant Human CD144/CDH5 Protein, C-Fc (PX-P6186) expressed in Mammalian Cells, Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 表达系统 | Mammalian Cells |
| Accession号 | P33151 |
| 蛋白长度 | Met1-Gln593 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 93.06 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | 7B4 antigen, CD144, VE-cadherin, Cadherin-5, CDH5, Vascular endothelial cadherin |
| 背景 | Cadherin-5 (CD144/CDH5) is a ~87 kDa protein. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Plays a role in coupling actin fibers to cell junctions in endothelial cells, via acting as a cell junctional complex anchor for AMOTL2 and MAGI1. 1. Brasch, J. et al. (2011) Journal of molecular biology 408, 57-73. PMID: 21269602 2. Shimoyama, Y. et al. (2000) The Biochemical journal 349, 159-67. PMID: 10861224 3. Lampugnani, MG. et al. (2010) Journal of cell science 123, 1073-80. PMID: 20332120 4. Abiko, H. et al. (2015) Journal of cell science 128, 1683-95. PMID: 25795300 |
| Note | For research use only. |

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