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Recombinant Human CD215/IL15RA Protein, C-Fc (PX-P6203)

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概述
货号PX-P6203
品牌ProteoGenix
描述
Recombinant Human CD215/IL15RA Protein, C-Fc (PX-P6203) expressed in Mammalian Cells, Purity: >90% as determined by SDS-PAGE..
Highlights
  • High Purity (>90% as determined by SDS-PAGE.) — Verified by SDS-PAGE for downstream accuracy.
  • Mammalian Cells Expression — Optimized for functional studies.
表达系统Mammalian Cells
Accession号Q13261
蛋白长度Ile31-Thr205
应用ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属Homo sapiens (Human)
性质Recombinant
内毒素水平Please contact with the lab for this information.
纯度>90% as determined by SDS-PAGE.
预测分子量48.02 kDa
状态Lyophilized
保存溶液 Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名IL-15 receptor subunit alpha, sIL-15R-alpha, IL-15RA, CD215, sIL-15 receptor subunit alpha, Interleukin-15 receptor subunit alpha, IL-15R-alpha, sIL-15RA, IL15RA
背景

Interleukin-15 receptor subunit alpha (CD215/IL15RA) is a ~28 kDa protein. High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. In neutrophils, binds and activates kinase SYK in response to IL15 stimulation. In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner. Expression of different isoforms may alter or interfere with signal transduction.

1. Anderson, DM. et al. (1995) The Journal of biological chemistry 270, 29862-9. PMID: 8530383
2. Ratthé, C. et al. (2004) Journal of leukocyte biology 76, 162-8. PMID: 15123770
3. Dubois, S. et al. (1999) The Journal of biological chemistry 274, 26978-84. PMID: 10480910
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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