

| 货号 | PX-P6228 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Recombinant Human CD320 Protein, C-Fc (PX-P6228) expressed in Mammalian Cells, Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 表达系统 | Mammalian Cells |
| Accession号 | Q9NPF0 |
| 蛋白长度 | Met1-Gly208 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 47.87 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | FDC-SM-8D6, FDC-signaling molecule 8D6, CD320, TCblR, 8D6 antigen, 8D6A, Transcobalamin receptor, CD320 antigen |
| 背景 | CD320 antigen is a ~28 kDa protein. Receptor for transcobalamin saturated with cobalamin (TCbl). Plays an important role in cobalamin uptake. Plasma membrane protein that is expressed on follicular dendritic cells (FDC) and mediates interaction with germinal center B cells. Functions as costimulator to promote B cell responses to antigenic stimuli; promotes B cell differentiation and proliferation. Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). 1. Quadros, EV. et al. (2009) Blood 113, 186-92. PMID: 18779389 2. Quadros, EV. et al. (2010) Human mutation 31, 924-9. PMID: 20524213 3. Li, L. et al. (2000) The Journal of experimental medicine 191, 1077-84. PMID: 10727470 4. Zhang, X. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 49-56. PMID: 11418631 |
| Note | For research use only. |

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