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Recombinant Human CD320 Protein, C-Fc (PX-P6228)

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概述
货号PX-P6228
品牌ProteoGenix
描述
Recombinant Human CD320 Protein, C-Fc (PX-P6228) expressed in Mammalian Cells, Purity: >90% as determined by SDS-PAGE..
Highlights
  • High Purity (>90% as determined by SDS-PAGE.) — Verified by SDS-PAGE for downstream accuracy.
  • Mammalian Cells Expression — Optimized for functional studies.
表达系统Mammalian Cells
Accession号Q9NPF0
蛋白长度Met1-Gly208
应用ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属Homo sapiens (Human)
性质Recombinant
内毒素水平Please contact with the lab for this information.
纯度>90% as determined by SDS-PAGE.
预测分子量47.87 kDa
状态Lyophilized
保存溶液 Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名FDC-SM-8D6, FDC-signaling molecule 8D6, CD320, TCblR, 8D6 antigen, 8D6A, Transcobalamin receptor, CD320 antigen
背景

CD320 antigen is a ~28 kDa protein. Receptor for transcobalamin saturated with cobalamin (TCbl). Plays an important role in cobalamin uptake. Plasma membrane protein that is expressed on follicular dendritic cells (FDC) and mediates interaction with germinal center B cells. Functions as costimulator to promote B cell responses to antigenic stimuli; promotes B cell differentiation and proliferation. Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC).

1. Quadros, EV. et al. (2009) Blood 113, 186-92. PMID: 18779389
2. Quadros, EV. et al. (2010) Human mutation 31, 924-9. PMID: 20524213
3. Li, L. et al. (2000) The Journal of experimental medicine 191, 1077-84. PMID: 10727470
4. Zhang, X. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 49-56. PMID: 11418631
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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