Recombinant Human CD208/LAMP3 Protein, C-His (PX-P6234)
概述
图片
参考文献
概述
货号
PX-P6234
品牌
ProteoGenix
描述
Recombinant Human CD208/LAMP3 Protein, C-His (PX-P6234) expressed in Mammalian Cells, Purity: >90% as determined by SDS-PAGE..
Highlights
High Purity (>90% as determined by SDS-PAGE.) — Verified by SDS-PAGE for downstream accuracy.
Mammalian Cells Expression — Optimized for functional studies.
表达系统
Mammalian Cells
Accession号
Q9UQV4
蛋白长度
Met1-Thr381
应用
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
41.52 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
DCLAMP, CD208, LAMP-3, LAMP3, Lysosomal-associated membrane protein 3, TSC403, Lysosome-associated membrane glycoprotein 3, DC LAMP, Protein TSC403, DC-lysosome-associated membrane glycoprotein
背景
Lysosome-associated membrane glycoprotein 3 (CD208/LAMP3) is a ~44 kDa protein. Lysosomal membrane glycoprotein which plays a role in the unfolded protein response (UPR) that contributes to protein degradation and cell survival during proteasomal dysfunction. Plays a role in the process of fusion of the lysosome with the autophagosome, thereby modulating the autophagic process. Promotes hepatocellular lipogenesis through activation of the PI3K/Akt pathway. May also play a role in dendritic cell function and in adaptive immunity.
1. Dominguez-Bautista, JA. et al. (2015) European journal of cell biology 94, 148-61. PMID: 25681212
2. Nagelkerke, A. et al. (2014) Endocrine-related cancer 21, 101-12. PMID: 24434718
3. Liao, X. et al. (2018) Molecular and cellular endocrinology 470, 160-167. PMID: 29056532
4. de Saint-Vis, B. et al. (1998) Immunity 9, 325-36. PMID: 9768752
