Recombinant Mouse IL18 Protein, C-Fc (PX-P4661)

概述
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参考文献

概述

货号	PX-P4661
品牌	ProteoGenix
描述	Recombinant Mouse IL18 Protein, C-Fc (PX-P4661) expressed in Mammalian Cells, Purity: >90% as determined by SDS-PAGE.. Highlights High Purity (>90% as determined by SDS-PAGE.) — Verified by SDS-PAGE for downstream accuracy. Mammalian Cells Expression — Optimized for functional studies.
表达系统	Mammalian Cells
Accession号	P70380
蛋白长度	Met1-Ser192
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Mus musculus (Mouse)
性质	Recombinant
内毒素水平	Please contact with the lab for this information.
纯度	>90% as determined by SDS-PAGE.
预测分子量	47.70 kDa
状态	Lyophilized
保存溶液	Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	Interleukin-18, IL-18, Interferon gamma-inducing factor, IFN-gamma-inducing factor, Interleukin-1 gamma, IL-1 gamma, Il18, Igif
背景	Interleukin-18 (IL18/IL1F4) is a ~22 kDa protein. Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. 1. Levy, M. et al. (2015) Cell 163, 1428-43. PMID: 26638072 2. Nowarski, R. et al. (2015) Cell 163, 1444-56. PMID: 26638073 3. Hara, H. et al. (2018) Cell 175, 1651-1664.e14. PMID: 30392956
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Recombinant Mouse IL18 Protein, C-Fc (PX-P4661)

概述

图片

参考文献

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重组蛋白

抗体

试剂盒

实验相关试剂

Recombinant Mouse IL18 Protein, C-Fc (PX-P4661)

概述

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参考文献

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