

| 货号 | PX-P5871 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Recombinant Human Osteocalcin/BGLAP/OC Protein, N-His (PX-P5871) expressed in E. coli, Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 表达系统 | E. coli |
| Accession号 | P02818 |
| 蛋白长度 | Lys24-Val100 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 11.06 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | Gamma-carboxyglutamic acid-containing protein, BGLAP, BGP, Bone Gla protein, Osteocalcin |
| 背景 | Osteocalcin (BGLAP) is a ~10 kDa protein. The carboxylated form is one of the main organic components of the bone matrix, which constitutes 1-2% of the total bone protein. Acts as a negative regulator of bone formation and is required to limit bone formation without impairing bone resorption or mineralization. Binds strongly to apatite and calcium upon gamma-carboxylation; this modification is essential for bone metabolism. 1. Celeste, AJ. et al. (1986) The EMBO journal 5, 1885-90. PMID: 3019668 2. Poser, JW. et al. (1980) The Journal of biological chemistry 255, 8685-91. PMID: 6967872 3. Wang, R. et al. (2025) Nature 639, 808-815. PMID: 39880952 |
| Note | For research use only. |

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