Recombinant Human HSPB1/HSP27 Protein, N-His (PX-P5758)
概述
图片
参考文献
概述
货号
PX-P5758
品牌
ProteoGenix
描述
Recombinant Human HSPB1/HSP27 Protein, N-His (PX-P5758) expressed in E. coli, Purity: >90% as determined by SDS-PAGE..
Highlights
High Purity (>90% as determined by SDS-PAGE.) — Verified by SDS-PAGE for downstream accuracy.
E. coli Expression — Optimized for functional studies.
表达系统
E. coli
Accession号
P04792
蛋白长度
Met1-Lys205
应用
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
25.09 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Heat shock protein beta-1 (HSPB1/HSP27) is a ~22 kDa protein. Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Plays a role in stress resistance and actin organization. Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins.
1. Rogalla, T. et al. (1999) The Journal of biological chemistry 274, 18947-56. PMID: 10383393
2. Almeida-Souza, L. et al. (2010) The Journal of biological chemistry 285, 12778-86. PMID: 20178975
3. Kostenko, S. et al. (2009) Cellular signalling 21, 712-8. PMID: 19166925
4. Holmgren, A. et al. (2013) Acta neuropathologica 126, 93-108. PMID: 23728742
