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Recombinant Human KRT18 Protein, N-His (PX-P5810)

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概述
货号PX-P5810
品牌ProteoGenix
描述
Recombinant Human KRT18 Protein, N-His (PX-P5810) expressed in E. coli, Purity: >90% as determined by SDS-PAGE..
Highlights
  • High Purity (>90% as determined by SDS-PAGE.) — Verified by SDS-PAGE for downstream accuracy.
  • E. coli Expression — Optimized for functional studies.
表达系统E. coli
Accession号P05783
蛋白长度Asp238-Leu396
应用ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属Homo sapiens (Human)
性质Recombinant
内毒素水平Please contact with the lab for this information.
纯度>90% as determined by SDS-PAGE.
预测分子量20.44 kDa
状态Lyophilized
保存溶液 Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬Reconstitute in sterile water for a stock solution.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名Cytokeratin-18, CYK18, K18, Keratin, type I cytoskeletal 18, KRT18, CK-18, Keratin-18, Cell proliferation-inducing gene 46 protein
背景

Keratin, type I cytoskeletal 18 (KRT18) is a ~48 kDa protein. Required for the formation of KRT8/KRT18 filaments that are involved in ARHGEF40-mediated actin stress fiber formation and tensional force-induced stress fiber formation and reinforcement. Also acts downstream of ROCK kinase activation as part of a positive feedback mechanism in response to cellular mechanical stress loading. Organization and orientation of KRT18 filaments are responsible for the properly elongated morphology of epithelial tubules. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. When phosphorylated, plays a role in filament reorganization.

1. Fujiwara, S. et al. (2016) Molecular biology of the cell 27, 954-66. PMID: 26823019
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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