

| 货号 | PX-P5990 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Recombinant Mouse MIF/GIF Protein, N-His (PX-P5990) expressed in E. coli, Purity: >80% as determined by SDS-PAGE..
Highlights
|
| 表达系统 | E. coli |
| Accession号 | P34884 |
| 蛋白长度 | Met1-Ala115 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Mus musculus (Mouse) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >80% as determined by SDS-PAGE. |
| 预测分子量 | 14.67 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | MIF, L-dopachrome isomerase, L-dopachrome tautomerase, GIF, Macrophage migration inhibitory factor, MMIF, Phenylpyruvate tautomerase, Glycosylation-inhibiting factor, GLIF |
| 背景 | Macrophage migration inhibitory factor (MIF/GIF) is a ~12 kDa protein. Pro-inflammatory cytokine involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. 1. Stamps, SL. et al. (2000) Biochemistry 39, 9671-8. PMID: 10933783 2. Golubkov, PA. et al. (2006) Bioorganic chemistry 34, 183-99. PMID: 16780921 3. Fingerle-Rowson, G. et al. (2009) Molecular and cellular biology 29, 1922-32. PMID: 19188446 |
| Note | For research use only. |

24小时产品查询

扫一扫关注我们

专属渠道经理