

| 货号 | PX-P5484 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Recombinant Human ANP32B Protein, N-His (PX-P5484) expressed in E. coli, Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 表达系统 | E. coli |
| Accession号 | Q92688 |
| 蛋白长度 | Met1-Glu151 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 19.40 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | Acidic leucine-rich nuclear phosphoprotein 32 family member B; Acidic protein rich in leucines; Putative HLA-DR-associated protein I-2; PHAPI2; Silver-stainable protein SSP29; ANP32B; APRIL; PHAPI2 |
| 背景 | Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) is a ~28 kDa protein. Multifunctional protein that is involved in the regulation of many processes including cell proliferation, apoptosis, cell cycle progression or transcription. Regulates the proliferation of neuronal stem cells, differentiation of leukemic cells and progression from G1 to S phase of the cell cycle. As negative regulator of caspase-3-dependent apoptosis, may act as an antagonist of ANP32A in regulating tissue homeostasis. Exhibits histone chaperone properties, able to recruit histones to certain promoters, thus regulating the transcription of specific genes. Also plays an essential role in the nucleocytoplasmic transport of specific mRNAs via the uncommon nuclear mRNA export receptor XPO1/CRM1. 1. Munemasa, Y. et al. (2008) Molecular and cellular biology 28, 1171-81. PMID: 18039846 2. Shen, SM. et al. (2010) Carcinogenesis 31, 419-26. PMID: 20015864 3. Tochio, N. et al. (2010) Journal of molecular biology 401, 97-114. PMID: 20538007 4. Fries, B. et al. (2007) The Journal of biological chemistry 282, 4504-4515. PMID: 17178712 |
| Note | For research use only. |

24小时产品查询

扫一扫关注我们

专属渠道经理