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Recombinant RABV G/Glycoprotein, C-His (PX-P4466)

概述
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参考文献

概述

货号	PX-P4466
品牌	ProteoGenix
描述	Recombinant RABV G/Glycoprotein, C-His (PX-P4466) expressed in Mammalian Cells, Purity: >90% as determined by SDS-PAGE.. Highlights High Purity (>90% as determined by SDS-PAGE.) — Verified by SDS-PAGE for downstream accuracy. Mammalian Cells Expression — Optimized for functional studies.
表达系统	Mammalian Cells
Accession号	P08667
蛋白长度	Met1-Leu524
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Rabies virus (RABV)
性质	Recombinant
内毒素水平	Please contact with the lab for this information.
纯度	>90% as determined by SDS-PAGE.
预测分子量	60.01 kDa
状态	Liquid
保存溶液	50mM Tris-HCl pH 7.4, 150mM NaCl, 10% Glycerol, 4mM EDTA, 0.1% CHAPS. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	G, Glycoprotein
背景	Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. 1. Wang, J. et al. (2018) PLoS pathogens 14, e1007189. PMID: 30028877 2. Shuai, L. et al. (2020) Journal of virology 94. PMID: 31666383 3. Wang, X. et al. (2023) Journal of virology 97, e0161222. PMID: 36779762
Note	For research use only.

图片

参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Recombinant RABV G/Glycoprotein, C-His

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