

| 货号 | PX-P6209 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Recombinant Human AOC3/VAP-1 Protein, C-His (PX-P6209) expressed in Insect Cells, Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 表达系统 | Insect Cells |
| Accession号 | Q16853 |
| 蛋白长度 | Gly27-Asn763 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 84.75 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | Membrane primary amine oxidase, AOC3, SSAO, Semicarbazide-sensitive amine oxidase, Vascular adhesion protein 1, VAP-1, HPAO, Copper amine oxidase, VAP1 |
| 背景 | Amine oxidase [copper-containing] 3 (AOC3/VAP-1) is a ~84 kDa protein. Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Has a preference for the primary monoamines methylamine and benzylamine. Could also act on 2-phenylethylamine but much less efficiently. At endothelial cells surface can also function as a cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. 1. Kaitaniemi, S. et al. (2009) Cellular and molecular life sciences : CMLS 66, 2743-57. PMID: 19588076 2. Bligt-Lindén, E. et al. (2013) Journal of medicinal chemistry 56, 9837-48. PMID: 24304424 3. Smith, DJ. et al. (1998) The Journal of experimental medicine 188, 17-27. PMID: 9653080 4. Salmi, M. et al. (1997) The Journal of experimental medicine 186, 589-600. PMID: 9254657 |
| Note | For research use only. |

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