Recombinant Human DHX36/MLEL1 Protein, N-GST & C-His (PX-P6086)
概述
图片
参考文献
概述
货号
PX-P6086
品牌
ProteoGenix
描述
Recombinant Human DHX36/MLEL1 Protein, N-GST & C-His (PX-P6086) expressed in E. coli, Purity: >90% as determined by SDS-PAGE..
Highlights
High Purity (>90% as determined by SDS-PAGE.) — Verified by SDS-PAGE for downstream accuracy.
E. coli Expression — Optimized for functional studies.
表达系统
E. coli
Accession号
Q9H2U1
蛋白长度
Ser136-Lys988
应用
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
125.95 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
KIAA1488, DHX36, MLE-like protein 1, RNA helicase associated with AU-rich element protein, G4R1, MLEL1, DEAD/H box polypeptide 36, ATP-dependent DNA/RNA helicase DHX36, RHAU, DDX36, DEAH-box protein 36, G4-resolvase-1
背景
ATP-dependent DNA/RNA helicase DHX36 (MLEL1) is a ~114 kDa protein. Multifunctional ATP-dependent helicase that unwinds G-quadruplex (G4) structures. Plays a role in many biological processes such as genomic integrity, gene expression regulations and as a sensor to initiate antiviral responses. G4 structures correspond to helical structures containing guanine tetrads. Binds with high affinity to and unwinds G4 structures that are formed in nucleic acids (G4-DNA and G4-RNA). Plays a role in genomic integrity.
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