Recombinant Human FST/Follistatin Protein, C-Fc (PX-P6312)

概述
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参考文献

概述

货号	PX-P6312
品牌	ProteoGenix
描述	Recombinant Human FST/Follistatin Protein, C-Fc (PX-P6312) expressed in Mammalian Cells, Purity: >90% as determined by SDS-PAGE.. Highlights High Purity (>90% as determined by SDS-PAGE.) — Verified by SDS-PAGE for downstream accuracy. Mammalian Cells Expression — Optimized for functional studies.
表达系统	Mammalian Cells
Accession号	P19883
蛋白长度	Met30-Lys344
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Homo sapiens (Human)
性质	Recombinant
内毒素水平	Please contact with the lab for this information.
纯度	>90% as determined by SDS-PAGE.
预测分子量	60.33 kDa
状态	Lyophilized
保存溶液	Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	Activin-binding protein, FS, FST, Follistatin
背景	Follistatin (FST) is a ~38 kDa protein. Multifunctional regulatory protein whose primary function is to antagonize members of the transforming growth factor beta (TGF-beta) superfamily including activin, myostatin, GDF11 or bone morphogenetic proteins (BMPs). Mechanistically, binds to these ligands in the extracellular space, blocking their type II receptor-binding site to inhibit downstream signaling. Plays an essential role in muscle fiber formation and growth both by preventing the repressive effects of myostatin and through SMAD3/AKT/mTOR signaling independently of myostatin. Also promotes neural differentiation by antagonizing the action BMP4. Acts as a specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH) by sequestering activin A/INHBA. 1. Sidis, Y. et al. (2001) The Journal of biological chemistry 276, 17718-26. PMID: 11279126 2. Harrington, AE. et al. (2006) The EMBO journal 25, 1035-45. PMID: 16482217 3. Schneyer, AL. et al. (2008) Endocrinology 149, 4589-95. PMID: 18535106
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Recombinant Human FST/Follistatin Protein, C-Fc (PX-P6312)

概述

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重组蛋白

抗体

试剂盒

实验相关试剂

Recombinant Human FST/Follistatin Protein, C-Fc (PX-P6312)

概述

图片

参考文献

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