Recombinant Human LY96 Protein, C-Fc (PX-P6433) expressed in Mammalian Cells, Purity: >90% as determined by SDS-PAGE..
Highlights
High Purity (>90% as determined by SDS-PAGE.) — Verified by SDS-PAGE for downstream accuracy.
Mammalian Cells Expression — Optimized for functional studies.
表达系统
Mammalian Cells
Accession号
Q9Y6Y9
蛋白长度
Met1-Asn160
应用
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
44.95 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
Ly-96, ESOP-1, MD2, Lymphocyte antigen 96, Protein MD-2, LY96, ESOP1
背景
Lymphocyte antigen 96 (LY96) is a ~18 kDa protein. Binds bacterial lipopolysaccharide (LPS). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS.
1. Ohto, U. et al. (2007) Science (New York, N.Y.) 316, 1632-4. PMID: 17569869
2. Kim, HM. et al. (2007) Cell 130, 906-17. PMID: 17803912
3. Dziarski, R. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 166, 1938-44. PMID: 11160242
4. Visintin, A. et al. (2001) Proceedings of the National Academy of Sciences of the United States of America 98, 12156-61. PMID: 11593030
5. Shimazu, R. et al. (1999) The Journal of experimental medicine 189, 1777-82. PMID: 10359581
