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Recombinant Human Gal9/LGALS9 Protein, N-Fc (PX-P6440)

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概述
货号PX-P6440
品牌ProteoGenix
描述
Recombinant Human Gal9/LGALS9 Protein, N-Fc (PX-P6440) expressed in Mammalian Cells, Purity: >90% as determined by SDS-PAGE..
Highlights
  • High Purity (>90% as determined by SDS-PAGE.) — Verified by SDS-PAGE for downstream accuracy.
  • Mammalian Cells Expression — Optimized for functional studies.
表达系统Mammalian Cells
Accession号O00182
蛋白长度Ala2-Thr355
应用ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属Homo sapiens (Human)
性质Recombinant
内毒素水平Please contact with the lab for this information.
纯度>90% as determined by SDS-PAGE.
预测分子量63.34 kDa
状态Lyophilized
保存溶液 Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名Galectin-9, Gal-9, Ecalectin, Tumor antigen HOM-HD-21, LGALS9
背景

Galectin-9 (Gal-9) is a ~39 kDa protein. Binds galactosides. Has high affinity for the Forssman pentasaccharide. Ligand for HAVCR2/TIM3. Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death. Also stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth.

1. Nagae, M. et al. (2008) Journal of molecular biology 375, 119-35. PMID: 18005988
2. Zhu, C. et al. (2005) Nature immunology 6, 1245-52. PMID: 16286920
3. Bi, S. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 10650-5. PMID: 21670307
4. Gieseke, F. et al. (2013) European journal of immunology 43, 2741-9. PMID: 23817958
5. Mengshol, JA. et al. (2010) PloS one 5, e9504. PMID: 20209097
6. Dai, SY. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 2974-81. PMID: 16116184
7. Kojima, R. et al. (2014) PloS one 9, e86106. PMID: 24465902
9. Golden-Mason, L. et al. (2013) Journal of virology 87, 4835-45. PMID: 23408620
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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