

| 货号 | PX-P6535 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Recombinant Human IZUMO1R Protein, C-His (PX-P6535) expressed in Mammalian Cells, Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 表达系统 | Mammalian Cells |
| Accession号 | A6ND01 |
| 蛋白长度 | Gly20-Ser228 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 26.94 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | IZUMO1 receptor protein JUNO, JUNO, Sperm-egg fusion protein Juno, FOLR4, IZUMO1R, Folate receptor delta, FR-delta, Folate receptor 4 |
| 背景 | Sperm-egg fusion protein Juno (IZUMO1R) is a ~28 kDa protein. Receptor for IZUMO1 present at the cell surface of oocytes (oolemma), which is essential for species-specific gamete recognition and fertilization. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. Does not bind folate. 1. Jean, C. et al. (2019) Human reproduction (Oxford, England) 34, 118-126. PMID: 30517645 |
| Note | For research use only. |

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