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Recombinant Human PDE6D Protein, C-Fc (PX-P6536)

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概述
货号PX-P6536
品牌ProteoGenix
描述
Recombinant Human PDE6D Protein, C-Fc (PX-P6536) expressed in Mammalian Cells, Purity: >90% as determined by SDS-PAGE..
Highlights
  • High Purity (>90% as determined by SDS-PAGE.) — Verified by SDS-PAGE for downstream accuracy.
  • Mammalian Cells Expression — Optimized for functional studies.
表达系统Mammalian Cells
Accession号O43924
蛋白长度Met1-Val150
应用ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属Homo sapiens (Human)
性质Recombinant
内毒素水平Please contact with the lab for this information.
纯度>90% as determined by SDS-PAGE.
预测分子量45.88 kDa
状态Lyophilized
保存溶液 Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名PDE6D, Protein p17, GMP-PDE delta, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, PDED
背景

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) is a ~17 kDa protein. Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Required for RAB28 localization to the cone cell outer segments in the retina. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI).

1. Marzesco, AM. et al. (1998) The Journal of biological chemistry 273, 22340-5. PMID: 9712853
2. Ismail, SA. et al. (2011) Nature chemical biology 7, 942-9. PMID: 22002721
3. Zimmermann, G. et al. (2013) Nature 497, 638-42. PMID: 23698361
4. Thomas, S. et al. (2014) Human mutation 35, 137-46. PMID: 24166846
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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