

| 货号 | PX-P4827 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Recombinant Human PTPRN Protein, N-MAT (PX-P4827) expressed in E. coli, Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 表达系统 | E. coli |
| Accession号 | Q16849 |
| 蛋白长度 | His603-Gln979 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 44.79 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | ICA512-TMF, ICA512-CCF, Receptor-type tyrosine-protein phosphatase-like N, Islet cell autoantigen 3, ICA512, PTPRN, Islet cell antigen 512, ICA 512, PTP IA-2, ICA3, ICA512-NTF, R-PTP-N |
| 背景 | Receptor-type tyrosine-protein phosphatase-like N (PTPRN) is a ~105 kDa protein. Plays a role in vesicle-mediated secretory processes. Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancreatic islets. Required for the accumulation of normal levels of insulin-containing vesicles and preventing their degradation. Plays a role in insulin secretion in response to glucose stimuli. Required for normal accumulation of the neurotransmitters norepinephrine, dopamine and serotonin in the brain. 1. Harashima, S. et al. (2012) Journal of diabetes investigation 3, 52-61. PMID: 24843546 |
| Note | For research use only. |

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