Recombinant Human SCARB1/SR-BI/CLA-1/SRB1 Protein, C-His (PX-P6114)
概述
图片
参考文献
概述
货号
PX-P6114
品牌
ProteoGenix
描述
Recombinant Human SCARB1/SR-BI/CLA-1/SRB1 Protein, C-His (PX-P6114) expressed in Mammalian Cells, Purity: >90% as determined by SDS-PAGE..
Highlights
High Purity (>90% as determined by SDS-PAGE.) — Verified by SDS-PAGE for downstream accuracy.
Mammalian Cells Expression — Optimized for functional studies.
表达系统
Mammalian Cells
Accession号
Q8WTV0
蛋白长度
Pro33-Tyr443
应用
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
49.63 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
CD36, CLA1, CD36 antigen-like 1, CD36L1, SRB1, Collagen type I receptor, thrombospondin receptor-like 1, SCARB1, Scavenger receptor class B member 1, CLA-1, SR-BI, CD36 and LIMPII analogous 1, SARS-like Coronaviruses
背景
Scavenger receptor class B member 1 (SCARB1/SR-BI) is a ~60 kDa protein. Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux. Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity.
1. Kawasaki, Y. et al. (2002) The Journal of biological chemistry 277, 27559-66. PMID: 12016218
2. Tai, ES. et al. (2003) Clinical genetics 63, 53-8. PMID: 12519372
3. Vergeer, M. et al. (2011) The New England journal of medicine 364, 136-45. PMID: 21226579
4. Zanoni, P. et al. (2016) Science (New York, N.Y.) 351, 1166-71. PMID: 26965621
